Kūʻai nui maʻemaʻe maʻemaʻe maoli Atractylodes Lancea aila no kēlā me kēia lā ʻoihana lāʻau lāʻau lāʻau ʻaila Atractylis.

ʻO ka pisthorchis viverrini (OV)-induced cholangiocarcinoma (CCA) ka maʻi maʻi maʻamau ma waena o ke kāne a me ka wahine, ʻoi aku ma Thailand. Ua hōʻike ʻia ka noiʻi hou ʻana ua hana ka ethanol extract o AL i kahi hopena pale i ka OV-induced CCA holoholona kŘkohu me ka ʻike ʻole ʻia o ka ʻawaʻawa ma o ka hoʻoponopono waha no nā lā 30 e like me nā hopena mai ka positron emission tomography-computed tomography a me nā male Syrian hamsters [7]. I mea e 'imi ai i ka hopena o ka AL rhizome ma ka gastrointestinal motility, ua apono 'ia ka atropine-, dopamine-, a me 5-hydroxytryptamine (5-HT) -treated mice i loko o ke a'o. ʻO nā hopena i hoʻoikaika ʻia e hiki i ka 1 mg/kg extract ke hoʻopau loa i ka dopamine-induced gastric emptying a me ka hoʻohaʻahaʻa ʻana o ka ʻōpū ma o ka intraperitoneal injection. Hiki i ka extract o 1000 mg/kg ke kaohi i ka emi ʻana o ka motility o ka ʻōpū liʻiliʻi i hoʻokomo ʻia i ka atropine, a hiki i ka extract o 500 mg/kg ke hoʻopaʻa ʻia i ka 5-HT-induced gastric emptying and small intestinal motility motility [8]. Hoʻohui ʻia, ua hoʻokō ʻo AL i ka hopena anti-gastric ulcer ma ke ʻano o ka ʻiole ma o ka hoʻemi ʻana i nā mea hoʻopuʻi inflammatory (ie tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8), IL-6), a me prostaglandin E2 (PGE2) a me ka hoʻonui ʻana i ka epidermal growth factor (EGF) a me trefoil factor2 (TFF2) [9]. ʻO nā maʻi fungal mai ka lepo i hoʻemi ʻia he 30% o nā hua o ka pī.10]. I kēia mau lā, ua hōʻike ʻia ʻo ka intercropping me nā pīni, hiki i ka AL ke hoʻopau i nā maʻi fungal i lawe ʻia e ka lepo ma o ka pale ʻanaʻO Fusarium oxysporumulu [11]. Ua hōʻike ʻo Petroleum ether (PE) mai AL i kahi hopena pale ma BGC-823 a me SGC-7901 nā pūnaewele maʻi ʻōpū o ke kanaka. Hiki i ka hapa PE ke hoʻoulu i ka apoptosis, ka hopu ʻana o ka cell cycle, a me nā loli hiki ke hoʻololi i ka transmembrane mitochondrial [12]. Ua hōʻike ʻia kahi hōʻike hou e hiki ai i ka MeOH extract o AL ke kāohi i ka hana nitric oxide (NO) i ka lipopolysaccharide-stimulated murine macrophage-like RAW264.7 cell a hoʻoulu i ka granulocyte-colony stimulating factor (G-CSF) huna i loko o ka murine maʻamau colonic epithelial MCE301 cell. ʻO NO he radical manuahi [13]. Ua ho'ohana ka ethanol extract o AL i ka hopena ho'opa'i ko'iko'i ma luna o ka lipase me ka IC50 9.06 µg/mL i loko o kahi hō'ike lipase pancreatic kanaka, a ua hō'ike i ka hopena anti-obesity ma luna o ka momona momona obesity mice kumu ho'ohālike ma ke ki'eki'e o ka 500 mg. /kg [14]. Ua hōʻike nā ʻāpana wai mai AL i ka hana antagonistic e kūʻē i ka serotonin receptors a me kahi hopena pale i ka 5-HT2A/2C agonist koho 1-(2,5-dimethoxy-4-iodophenyl) -2-aminopropane-induced head-twitch pane i nā ʻiole. [15]. ʻO nā wai wai mai AL i hōʻemi i ka triptolide-induced toxicity ma o ka hoʻoponopono iho o ka hōʻike hepatic o CYP3A. I kēia manawa, hiki i ka AL ke hoʻomaikaʻi i nā hopena anti-inflammatory o triptolide. Ua hōʻike ʻia kēia mau ʻike e hiki iā AL ke kāohi i ka ʻona a hoʻonui i ka hana therapeutic o triptolide ma o ka hui ʻana