Kūʻai nui nui 100% Pure Forsythiae Fructus aila Relax Aromatherapy Eucalyptus globulus

ʻO ke kumu kūʻai nui nui 100% Pure Forsythiae Fructus oil Relax Aromatherapy Eucalyptus globulus Kiʻi Hōʻikeʻike

wehewehe pōkole:

Forsythia suspensa(Thunb.) Vahl. (ʻOhana Oleaceae) he kumu lāʻau hoʻonaninani, a hoʻohana ʻia nā hua o ia mea ma ke ʻano he TCM kaulana "Forsythiae Fructus" (FF) (连翘in Chinese). Ua hōʻuluʻulu ʻia nā ʻano TCM o FF e like me ka ʻawaʻawa i ka ʻono, me kahi ʻano anu anuanu a me ka māmā, ka puʻuwai a i ʻole ka ʻōpū meridian mahele (Pharmacopoeia Commission of PRC, 2015), ua like kēlā mau hiʻohiʻona me ke ʻano o ka anti-inflammatory TCM, e like me Chen. a me Zhang (2014). I loko o ka lāʻau lapaʻau o Shennong, ua hoʻohana ʻia ka FF no ka mālama ʻana i ka pyrexia, mumū, gonorrhea, carbuncle a me erysipelas (Cho et al., 2011). Loaʻa nā ʻano ʻelua o ka FF, ʻo ka hua ʻōmaʻomaʻo ʻōmaʻomaʻo i kapa ʻia ʻo "Qingqiao" a ʻo ka melemele i oʻo loa i kapa ʻia ʻo "Laoqiao". Hoʻohana ʻia lāua ʻelua ma ke ʻano he kumu kūhelu o FF, akā naʻe, hoʻohana pinepine ʻia ʻo Qingqiao i nā ʻōlelo kuhikuhi TCM (Jia et al., 2015). ʻO nā wahi hana nui o FF ʻo Hebei, Shaanxi, Shanxi, Shandong, Anhui, Henan, Hubei, Jiangsu (mahi ʻia) a me Sichuan Provinces (Editorial Board of Flora of China, 1978).

Ma ka 2015 edition Chinese Pharmacopoeia, 114 Chinese medicinal preparations i loaʻa ka FF i helu ʻia, e like me Shuanghuanglian oral solution, Yinqiao Jiedu tablet, Niuhuang Shangqing tablets, etc (Pharmacopoeia Commission of PRC, 2015). Hōʻike nā noiʻi hou i kāna anti-inflammatory (Kim et al., 2003), antioxidant (CC Chen et al., 1999), antibacterial (Han et al., 2012), anti-cancer (Hu et al., 2007), anti -virus (Ko et al., 2005), anti-allergy (Hao et al., 2010), neuroprotective (S. Zhang et al., 2015) hopena,etc.ʻOiai ʻo ka hua wale nō i hoʻohana ʻia e like me TCM, ua hōʻike kekahi mau haʻawina i ka phytochemistry a me nā hopena pharmacological o nā lau (Ge et al., 2015, Zhang et al., 2015), pua (Takizawa et al., 1981) a me nā hua (Zhang et al. ., 2002) oF. hoʻopaʻapaʻa. No laila, ke hāʻawi nei mākou i kahi ʻike kikoʻī o ka ʻike i loaʻa oF. hoʻopaʻapaʻa, me ka hoʻohana kuʻuna, botany, phytochemistry, pharmacology, toxicity, pharmacokinetics and quality control. Eia kekahi, ua kūkākūkā ʻia nā ʻaoʻao o ka noiʻi e hiki mai ana.

Māhele ʻāpana

Hoʻohana kuʻuna

Ma nā kikokikona lāʻau lapaʻau Kina kahiko, ua hoʻopaʻa ʻia ʻo FF i mea pono i ka mālama ʻana i ka fistula ʻiole, scrofula, carbuncle, malignant ulcer, gall tumor, wela a me nā mea make (Shennong's herbal, Bencao Chongyuan, Bencao Zhengyi, Zhenglei Bencao). Wahi a nā poʻe kahiko kahiko, ʻoi aku ka maikaʻi o kēia lāʻau lapaʻau i ka hoʻomaʻemaʻe ʻana i ka wela o ka puʻuwai a me ka hoʻokuʻu ʻana i ka wela o ka ʻōpū a me ka ʻōpū. He therapeutic no ka mālama ʻana i ka stranguria, edema, qi stagnancy a me ke koko stasis.

Botany

F. hoʻopaʻapaʻa(Weeping Forsythia) he kumulāʻau deciduous nani i Kina, e ulu ana i kahi kiʻekiʻe o 3 m (Fig. 1). Loaʻa iā ia nā internodes puha me nā lālā palahalaha a i ʻole nā lālā pendule he melemele-ʻeleʻele a hina-ʻeleʻele paha ke kala. He maʻalahi nā lau, akā i kekahi manawa 3-foliolate. ʻO nā lau lau he ovate, ākea ovate, a i ʻole elliptic-ovate a me 2–10 × 1.5–5 cm2 ka nui me kahi poʻe poʻe a cuneate kumu a me kahi apex acute. ʻO nā ʻaoʻao ʻelua o nā lau he ʻōmaʻomaʻo, ʻulaʻula me ka ʻoi a i ʻole ke koʻikoʻi

Phytochemistry

I kēia mau lā, ua loaʻa nā pūhui 237 i lokoF. hoʻopaʻapaʻa, me 46 lignans (1–46), 31 phenylethanoid glycosides (47–77), 11 flavonoids (78–88), 80 terpenoids (89–168), 20 cyclohexylethanol derivatives (169–188), eono alkaloids (189–194). ), ʻehā steroidal (195-198) a me 39 mau pūhui ʻē aʻe (199-237). Ma waena o lākou, ʻelua ʻāpana (21-22) i hoʻokaʻawale ʻia mai nā pua oF. hoʻopaʻapaʻa, 19 mau ʻāpana (94–100, 107–111, 115–117, 198, 233–235) i hoʻokaʻawale ʻia mai nā lau oF. hoʻopaʻapaʻa, eha mau mea

Nā hopena anti-inflammatory

Kākoʻo nā hana anti-inflammatory o FF i kona hopena hoʻomaʻemaʻe wela (Guo et al., 2015). ʻO ka hoʻoulu ʻana he pane kino i ka infectious, allergic, a i ʻole ka hoʻoulu ʻana i ke kemika (Lee et al., 2011). Hoʻopili ia i ka ulu ʻana o nā maʻi maʻi mau, e like me nā maʻi ʻili, nā allergies, a me ka maʻi kanesa,etc.ʻO FF kekahi o TCM me nā mana anti-inflammatory potent, ua hoʻohana nui ʻia i ka maʻi maʻi a me ka maʻi ʻeha. ʻO nā hana anti-inflammatory o FF i helu ʻia ma luna o ʻelima ma waena o 81 TCM i hoʻāʻo ʻia (70% ethanol

Kaʻawaʻawa

A hiki i kēia manawa, ʻaʻohe hōʻike e pili ana i ka ʻona o FF. Manaʻo ʻia ʻo 6-15 g (Pharmacopoeia Commission of PRC, 2015). Ua hōʻike ʻia nā hōʻike pili ʻaʻohe mea ʻawaʻawa o ka wai a i ʻole ethanol extract o nā lau oF. hoʻopaʻapaʻai nāʻiole,ʻoiai i kēlā me kēia lā o 61.60 g / kg (Ai et al., 2011, Hou et al., 2016, Li et al., 2013). Han et al. (2017) hōʻike ʻaʻohe mea ʻawaʻawa o ka phillyrin (mai nā lau oF. suspensa)i nā ʻiole NIH (18.1 g/kg/lā, po, no nā lā 14) a i ʻole

Pharmacokinetics

Li et al. ua ʻike ʻia nā metabolites ʻeiwa o ka phillyrin i loko o nā ʻano mimi o nā ʻiole a hōʻike i kāna mau ala metabolic hiki i nā ʻiole. Ua hoʻokahe ʻia ʻo Phillyrin i ka phillygenin a laila hoʻololi ʻia i nā metabolites ʻē aʻe ma o ka methylation, demethylation, dehydroxylation a me nā kaʻina hana hoʻoheheʻe apo (Li et al., 2014c). H. Wang et al. (2016) ua ʻike ʻia he 34 mau metabolites o ka phillyrin a me ka phase II a ua hōʻike ʻia he nui ka hydrolysis, oxidation a me ka sulfation.

Ka hoomalu maikai

No ka mālama ʻana i ka maikaʻi o ka FF, hōʻike ka Chinese Pharmacopoeia i ka morphological, microscopic a me TLC identification me ka hoʻoholo HPLC. Pono nā laʻana FF kūpono ma mua o 0.150% phillyrin (Pharmacopoeia Commission of PRC, 2015).

Eia naʻe, ʻaʻole lawa ka māka helu helu hoʻokahi, ʻo phillyrin, e nānā i ka maikaʻi o FF. I kēia mau lā, ua nānā ʻia nā ʻāpana bioactive like ʻole i ka FF e ka chromatography kūʻokoʻa, electrophoresis, MS a me nā ʻano NMR, e like me

Ka hopena a me nā manaʻo e hiki mai ana

Hōʻuluʻulu ka loiloi o kēia manawa i ka ʻike piha e pili ana i ka hoʻohana kuʻuna, botany, phytochemistry, hopena pharmaceutical, toxicity, pharmacokinetics a me ka hoʻomalu maikaʻi oF. hoʻopaʻapaʻa. Ma nā kikokikona lāʻau lapaʻau Kina kahiko a me ka Pharmacopoeia Kina, hoʻohana nui ʻia ka FF no ka hoʻomaʻemaʻe wela a me ka hoʻomaʻemaʻe. A hiki i kēia manawa, ʻoi aku ma mua o 230 mau pūhui i hoʻokaʻawale ʻia a ʻike ʻia mai kēia mea kanu. I waena o lākou, ua manaʻo ʻia nā lignans a me nā glycosides phenylethanoid e like me ke ʻano a me ka bioactive

Nā wehewehe TCM

ʻO Yin: ʻO "Yin" kekahi o nā pūʻali ʻokoʻa ʻelua o ke ʻano o ke ʻano, e like me ka hana kahiko o Kina o ke ao holoʻokoʻa. Hōʻike ʻia ʻo "Yin" ma ke ʻano he lohi, palupalu, hāʻawi, pālahalaha, anuanu, pulu a mālie paha, a pili pū me ka wai, ka honua, ka mahina, ka wahine a me ka pō.

Qi: Ma nā ʻōlelo acupuncture, "qi" ka "ola ola". ʻO ia ke kumu o nā neʻe a pau i loko o ke kino, ka pale ʻana i ka hoʻouka ʻana i ke kino, ke kumu o nā hana metabolic āpau, hoʻolako i ka paʻa ʻana o nā ʻiʻo.

Hoʻomaikaʻi

Kākoʻo ʻia kēia hana e ka Beijing Joint Project of Science Research me ka hoʻonaʻauao postgraduate–Ka noiʻi ʻenehana koʻikoʻi a me ka hoʻohana ʻana i ka loiloi palekana o nā lāʻau lapaʻau Kina ʻona e pili ana i ka haku mele a me nā ʻano o ka iʻa zebra.

Kumukuai FOB:US $0.5 - 9,999 / ʻāpana

Min.Kauoha Nui:100 ʻāpana/ ʻāpana

Hiki ke hoolako:10000 ʻāpana / ʻāpana i kēlā me kēia mahina

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Ethnopharmacological pili

Forsythiae Fructus (kapa ʻia ʻo Lianqiao ma ka ʻōlelo Pākē), ka hua oForsythia suspensa(Thunb.) Vahl, ua hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau maʻamau ma Kina, Iapana a me Korea. Hoʻohana maʻamau ia no ka mālama ʻana i ka pyrexia, ʻā,gonorrhea,kalaponaaerysipelas. Ma muli o ka manawa ohi like ʻole, hiki ke hoʻokaʻawale ʻia ʻo Forsythiae Fructus i ʻelua mau ʻano, ʻo ia ʻo Qingqiao a me Laoqiao. ʻO nā hua ʻōmaʻomaʻo e hoʻomaka ana e oʻo e hōʻiliʻili ʻia e like me Qingqiao, aʻo nā hua melemele i oʻo loa e hōʻiliʻili ʻia e like me Laoqiao. Hoʻohana ʻia nā mea ʻelua i ka hoʻohana lāʻau. Manaʻo kēia loiloi e hāʻawi i kahi hōʻuluʻulu ʻōnaehana oF. hoʻopaʻapaʻa(Forsythia suspensa(Thunb.) Vahl) a e hōʻike i ka pilina ma waena o nā hoʻohana kuʻuna a menā hana lāʻau lapaʻaui mea e hāʻawi ai i ka hoʻoikaika no ka noiʻi e hiki mai ana.

Nā mea a me nā ʻano hana

ʻO nā ʻike pili āpau e pili anaF. hoʻopaʻapaʻaua ʻimi ʻia e Scifinder a loaʻa mai nā ʻikepili ʻepekema me Springer, Science Direct, Wiley, Pubmed a me China Knowledge Resource Integrated (CNKI). Ua huli pū ʻia nā dissertation a me nā puke.

Nā hualoaʻa

Wahi a nā kikokikona lāʻau lapaʻau Kina kahiko a me ka Pharmacopoeia Kina, hōʻike nui ʻo Forsythiae Fructus i nā hopena hoʻomaʻemaʻe wela a me nā hopena detoxifying i loko.TCMpalapala kauoha. Ma ka noiʻi hou, ʻoi aku ma mua o 230 mau pūhui i hoʻokaʻawale ʻia a ʻike ʻia maiF. hoʻopaʻapaʻa. 211 Ua kaawale lakou i na hua.Lignansa me ka phenylethanoidnā glycosidesUa manaʻo ʻia ʻo ia nā ʻano a me nā mea ikaika o kēia mea kanu, e like me forsythiaside, phillyrin,hana maʻamaua me phillygenin. Ua hōʻike lākou i ka anti-inflammatory, antioxidant, antibacterial, anti-virus, anti-cancer and anti-allergy effects,etc.I kēia manawa, ʻaʻohe hōʻike e pili ana i ka ʻona o Forsythiae Fructus, ʻoiai he liʻiliʻi ʻona o ka forsythiaside i hōʻike ʻia ma nā puke kūloko. Hoʻohālikelike ʻia me Laoqiao, loaʻa iā Qingqiao nā pae kiʻekiʻe o forsythiaside, forsythoside C, cornoside,hana maʻamau, phillyrin,ʻakika gallicaʻakika chlorogenica me nā pae haʻahaʻa o ka rengyol,β- ka glucose a me ka S-suspensasidemethyl etera.

Ka hopena

Hoʻokumu ʻia nā hana hoʻomaʻemaʻe wela o Forsythiae Fructus ma luna o nā waiwai anti-inflammatory a antioxidant o lignans a me phenylethanoid.nā glycosides. ʻO nā hopena detoxifying e pili ana i nā hana antibacterial, antiviral a me anti-cancer o Forsythiae Fructus. A ʻo nā ʻano lāʻau lapaʻau Kina kuʻuna (TCM) o Forsythiae Fructus (ʻala ʻawaʻawa, ʻano anu liʻiliʻi a me ka meridian māmā) i kākoʻo i kona hopena anti-inflammatory ikaika. Eia kekahi, ka mea kupaianaha anti-inflammatory anā mana antioxidanto Forsythiae Fructus kōkua i kona anti-cancer aneuroprotectivenā hana. ʻO ka hapa kiʻekiʻe o nā lignans a me phenylethanoid glycosides ma Qingqiao ma mua o Laoqiao e wehewehe i ka hiki ke antioxidant maikaʻi o Qingqiao a me ka hoʻohana pinepine ʻana o Qingqiao i loko.TCMpalapala kauoha. No ka noiʻi hou akuin vivoHoʻoikaika ʻia nā hoʻokolohua a me nā noiʻi lapaʻau e wehewehe hou i ka pilina ma waena o nā hoʻohana kuʻuna a me nā noi hou. E pili ana iā Qingqiao a me Laoqiao, e hoʻokaʻawale ʻia lākou e nā ʻano hoʻokele maikaʻi a puni, a pono e hoʻohālikelike ʻia nā haku mele a me nā hopena lapaʻau ma waena o lākou.