ʻO ka aila ʻaila nui flos magnoliae no ka ʻaila ʻala

Maʻemaʻe maoli organika magnolia aila nui flos magnoliae aila no ka meaʻala ʻala Kiʻi

wehewehe pōkole:

ʻO Magnoliae Flos kahi lāʻau lapaʻau maʻamau ma Asia. Hoʻohana ʻia ia e mālama i ka sinusitis, nasal congestion, a me ka ʻili hypersensitive. No ka mea, ua wehewehe ʻia ʻo Magonlia Flos ma ke ʻano he mea ʻala i nā kikokikona Kina kahiko, ua manaʻo mākou e hiki ke hoʻohana ʻia kāna ʻaila koʻikoʻi no ka mālama ʻana i nā maʻi kūlohelohe. ʻO nā pūnaewele Dendritic (DCs), i manaʻo ʻia he pahuhopu nui o nā immunomodulators e hoʻomalu i nā pane kūlohelohe, pāʻani i ka hana koʻikoʻi i ka pane kūlohelohe adaptive. Ma kēia haʻawina, ua hoʻemi ka ʻaila nui o Magnoliae Flos (MFEO) i ka hana ʻana o nā cytokines TNF-α, IL-6, a me IL-12p70 i loko o ka lipopolysaccharide (LPS) -stimulated DCs. Ua hoʻopaʻa pū ʻia i nā māka ʻili MHC II, CD80, a me CD86 i nā DC i hoʻoulu ʻia e LPS. Ua hōʻike ʻia nā hiʻohiʻona holoholona i ka 2,4-Dinitro-1-fluorobenzene (DNFB) e hoʻoulu ai i kahi pane hypersensitivity hoʻopili ʻia ua kāohi ʻia ma hope o ka mālama ʻana me MFEO. Eia kekahi, ua kāohi ʻo MFEO i ka hoʻokomo ʻana o nā cell T i nā pepeiao o nā ʻiole DNFB. No ka ʻimi ʻana i kāna mau pūhui bioactive, ua kālailai ʻia nā ʻāpana o MFEO me ka hoʻohana ʻana i ke kinoea chromatography (GC) a me ka GC-mass spectrometry. Ua hōʻike ʻia nā hopena ʻo nā pūhui nui i MFEO he camphor a me 1,8-cineole. Ua hōʻoia ʻia nā bioassays DC hou i kēia mau pūhui i kaohi nui i ka hana cytokine ma LPS-induced DCs. No laila, ua hōʻike mākou e hōʻike ana ʻo MFEO i kahi hopena immunosuppressive ma vivo a me in vitro, a ʻo camphor a me 1,8-cineole paha nā mea nui e pili ana i kāna hiki immunosuppressive. Hōʻike nā ʻike he hiki ke hoʻomohala ʻia ka MFEO ma ke ʻano he immunosuppressant hou no nā maʻi nui.

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E hoʻouna i ka leka uila iā mākou

Huahana Huahana

, IL-6, a me IL-12p70 i ka lipopolysaccharide (LPS)-hoʻoulu DC. Ua hoʻopaʻa pū ʻia i nā māka ʻili MHC II, CD80, a me CD86 i nā DC i hoʻoulu ʻia e LPS. Ua hōʻike ʻia nā hiʻohiʻona holoholona i ka 2,4-Dinitro-1-fluorobenzene (DNFB) e hoʻoulu ai i kahi pane hypersensitivity hoʻopili ʻia ua kāohi ʻia ma hope o ka mālama ʻana me MFEO. Eia kekahi, ua kāohi ʻo MFEO i ka hoʻokomo ʻana o nā cell T i nā pepeiao o nā ʻiole DNFB. No ka ʻimi ʻana i kāna mau pūhui bioactive, ua kālailai ʻia nā ʻāpana o MFEO me ka hoʻohana ʻana i ke kinoea chromatography (GC) a me ka GC-mass spectrometry. Ua hōʻike ʻia nā hopena ʻo nā pūhui nui i MFEO he camphor a me 1,8-cineole. Ua hōʻoia ʻia nā bioassays DC hou i kēia mau pūhui i kaohi nui i ka hana cytokine ma LPS-induced DCs. No laila, ua hōʻike mākou e hōʻike ana ʻo MFEO i kahi hopena immunosuppressive ʻeluain vivoain vitro, a ʻo camphor a me 1,8-cineole paha nā mea nui e pili ana i kona hiki ke immunosuppressive. Hōʻike nā ʻike he hiki ke hoʻomohala ʻia ka MFEO ma ke ʻano he immunosuppressant hou no nā maʻi nui.