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Kūʻai nui maʻemaʻe maʻemaʻe maoli Atractylodes Lancea aila no kēlā me kēia lā ʻoihana lāʻau lāʻau lāʻau ʻaila Atractylis.
NĀ KĀNĀWAI O KA HOʻohana A ME KA ʻike nui: Ua manaʻo ʻia kēia ʻike e hoʻohui, ʻaʻole e hoʻololi i ka ʻōlelo aʻoaʻo mai kāu kauka a i ʻole mea mālama ola kino a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana āpau, ka mālama ʻana, ka pilina a i ʻole nā hopena ʻino. ʻAʻole kūpono paha kēia ʻike i kou kūlana olakino. Mai hoʻokaʻulua a hoʻowahāwahā paha i ka ʻimi ʻana i ka ʻōlelo aʻoaʻo lapaʻau ʻoihana mai kāu kauka a i ʻole kekahi mea mālama ola olakino ma muli o kahi mea āu i heluhelu ai ma WebMD. Pono ʻoe e kamaʻilio mau me kāu kauka a i ʻole ʻoihana mālama ola ma mua o kou hoʻomaka ʻana, hoʻōki, a hoʻololi paha i kekahi ʻāpana i kuhikuhi ʻia o kāu hoʻolālā mālama olakino a lapaʻau paha a e hoʻoholo i ke ʻano o ka lāʻau lapaʻau i kūpono iā ʻoe.
Hāʻawi ʻia kēia mea kope kope e Natural Medicines Comprehensive Database Consumer Version. ʻO ka ʻike mai kēia kumu he mea hōʻike a me ka pahuhopu, a me ka ʻole o ka mana ʻoihana. No ka 'ike lapa'au 'oihana e pili ana i nā lā'au maoli, e 'ike i ka Natural Medicines Comprehensive Database Professional Version.
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Kūʻai nui maʻemaʻe maʻemaʻe maoli Atractylodes Lancea aila no kēlā me kēia lā ʻoihana lāʻau lāʻau lāʻau ʻaila Atractylis.
He aha ka Atractylodes lancea root extract?
ʻO Atractylodes lancea kahi kumu Kina, lāʻau waiwai waiwai, i mahi ʻia no kāna rhizomes. Aia i loko o kona mau rhizomes nā aila pono.
Hoʻohana a me nā pono:
Loaʻa iā ia nā waiwai anti-inflammatory, hoʻomaha ia i ka ʻili ke hoʻohana ʻia. Hiki ke hoʻohana ʻia no ka ʻili ʻeha, ka ʻili ʻeha.
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ʻO ka aila Menthol CamphorBorneol no ka ʻauʻau a me ka ʻala
Nā Pono Ola a me nā hoʻohana
Hāʻawi ʻo Borneol i kahi hui maikaʻi loa o ka lāʻau lapaʻau Komohana a me Hikina. Ua laha ka hopena o Borneol i ka mālama ʻana i nā maʻi like ʻole. I ka lāʻau lapaʻau Kina, pili ia me ke ake, meridian spleen, puʻuwai, a me nā māmā. Aia ma lalo ka papa inoa o kekahi o kāna mau pono olakino.
E hakakā ana i ka maʻi hanu a me ka maʻi māmā
He nui nā haʻawina e hōʻike ana i ka terpenes, a me Borneol, ʻoi aku ka maikaʻi e hōʻemi i ka maʻi hanu. Ua loaʻa iā Borneolhōʻike maikaʻii ka ho'ēmiʻana i ka mumū o ka māmā ma o ka hoʻohaʻahaʻaʻana i nā cytokines inflammatory a me ka infiltration inflammatory. Hoʻohana maʻamau ka poʻe e hoʻomaʻamaʻa i ka lāʻau lapaʻau Kina i ka Borneol e mālama i ka bronchitis a me nā maʻi like ʻole.
Nā waiwai anticancer
Ua hōʻike pū ʻo Borneolwaiwai anticancerma ka hoʻonui ʻana i ka hana a Selenocysteine (SeC). Hoʻemi kēia i ka laha maʻi kanesa ma o ka make ʻana o ka maʻi maʻi maʻi apoptotic (programmed). I nā haʻawina he nui, ua hōʻike pū ʻo Borneol i ka hoʻonui ʻana i ka pono oʻimi lāʻau antitumor.
analgesic pono
Ma kahiao anae noʻonoʻo ana i ka ʻeha postoperative i loko o nā kānaka, ua alakaʻi ʻia ka noi Borneol topical i ka hōʻemi nui ʻana i ka ʻeha i hoʻohālikelike ʻia me kahi hui hoʻomalu placebo. Hoʻohui ʻia, hoʻohana nā acupuncturists i ka Borneol topically no kāna mau mea analgesic.
Ka hana anti-inflammatory
Ua loaʻa iā Borneolhōʻike ʻiake ālai ʻana i kekahi mau ala ion e hoʻoulu ai i ka ʻeha a me ka mumū. He kōkua nō hoʻi i ka hoʻomaha ʻana i ka ʻeha mai nā maʻi ʻeha e like merheumatoid arthritis.
Nā hopena neuroprotective
Hāʻawi ʻo Borneol i kahi pale maiʻo ka make ʻana o ka cell neuronali ka hopena o ka ischemic stroke. He mea maʻalahi hoʻi i ka hana hou ʻana o ka ʻiʻo lolo a hoʻoponopono. Manaʻo ʻia e loaʻa kēia hopena neuroprotective ma ka hoʻololi ʻana i ka permeability o kapale koko-lolo.
Paipai i ke kaumaha a me ka luhi
ʻO kekahi poʻe hoʻohana i nā kānana cannabis me nā kiʻekiʻe Borneol kiʻekiʻe e hōʻike ana e hoʻemi i ko lākou mau koʻikoʻi a hōʻemi i ka luhi, no laila e ʻae ai i kahi kūlana hoʻomaha me ka hoʻomaha ʻole. Hoʻomaopopo pū ka poʻe e hoʻomaʻamaʻa i ka lāʻau lapaʻau Kinakona mana hoʻomaha pilikial.
Ka hopena hui
E like me nā terpenes ʻē aʻe, ua hōʻike nā hopena o Borneol i hui pū me nā cannabinoids o ka cannabishopena hui.Hana ʻia kēia i ka wā e hana pū ai nā pūhui e hāʻawi i kahi pōmaikaʻi therapeutic kiʻekiʻe. Hiki i ka Borneol ke hoʻonui i ke kahe o ka pale koko-lolo, e ʻae ai i ka maʻalahi o ka hele ʻana o nā molekala lapaʻau i ka ʻōnaehana nerve waena.
Ma waho aʻe o ka nui o nā lāʻau lapaʻau o Borneol, hoʻohana mau ʻia ia i nā mea hoʻomaʻemaʻe pepeke ma muli o kona ʻona kūlohelohe i nā ʻōpala he nui. Hoʻohana nā mea ʻala i ka Borneol no kona ʻala ʻoluʻolu i ke kanaka.
Hiki i nā pilikia a me nā hopena ʻaoʻao
Manaʻo pinepine ʻia ʻo Borneol he terpene lua i ka cannabis, ʻo ia hoʻi ke ʻike ʻia ma nā liʻiliʻi liʻiliʻi. Ua manaʻo ʻia he palekana kēia mau haʻahaʻa haʻahaʻa o Borneol. Eia nō naʻe, i loko o nā haʻahaʻa kiʻekiʻe kaʻawale a i ʻole ka ʻike lōʻihi, hiki i Borneol ke loaʻa i kekahinā pilikia a me nā hopena ʻaoʻao, me:
- ʻIli ʻili
- ʻO ka huhū o ka ihu a me ka puʻu
- ʻEha poʻo
- Nausea a me ka luai
- Poniuniu
- Poʻo māmā
- Maule
Me ka ʻike kiʻekiʻe loa o Borneol, hiki i nā kānaka ke ʻike:
- Hoʻomaha ʻole
- ʻO ka hoʻohaunaele
- Ka nānā ʻole
- Hoʻopiʻi
- Inā ʻai ʻia, hiki ke lilo i mea ʻawaʻawa
He mea nui ia e hoʻomaopopo ʻaʻole hiki i ka nui o ka cannabis ke kumu i kēia mau hōʻailona. ʻAʻole loaʻa ka huhū me ka liʻiliʻi liʻiliʻi i hoʻohana ʻia no ka analgesia a me nā hopena ʻē aʻe.
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ʻO ka aila Cnidii Fructus maʻemaʻe no ke kukui a me ke kopa e hana ana i ka diffuser kūʻai nui i ka aila nui hou no nā diffusers kuni ʻohe.
He mea kanu ʻo Cnidium no Kina. Ua loaʻa nō hoʻi ia ma ka US ma Oregon. Hoʻohana ʻia ka hua, ka ʻanoʻano, a me nā mea kanu ʻē aʻe i lāʻau lapaʻau.
Ua hoʻohana ʻia ʻo Cnidium i ka lāʻau lapaʻau Kuʻuna Kina (TCM) no nā kaukani makahiki, pinepine no nā maʻi ʻili. ʻAʻole ia he mea kupanaha he mea maʻamau ka cnidium i nā lotions Kina, nā ʻaila, a me nā ʻaila.
Lawe ka poʻe i ka cnidium ma ka waha no ka hoʻonui ʻana i ka hana moe kolohe a me ka hoʻokalakupua, a no ka mālama ʻana i ka erectile dysfunction (ED). Hoʻohana pū ʻia ʻo Cnidium no ka paʻakikī o ka loaʻa ʻana o nā keiki (infertility), bodybuilding, cancer, iwi nāwaliwali (osteoporosis), a me nā maʻi fungal a me nā maʻi bacteria. Lawe kekahi poʻe e hoʻonui i ka ikehu.
Hoʻopili pololei ʻia ʻo Cnidium i ka ʻili no ka ʻili, ka ʻūhā, ka eczema, a me ka ʻili.
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ʻO ka ʻaila ʻala ʻala oud Branded no ke kukui a me ke kopa e hana ana i nā diffuser kūʻai nui i ka aila nui hou no nā mea hoʻoheheʻe puhi ʻohe.
ʻO ka hui kemika o ATR
ʻO ka hoʻohui kemika o ATR he mau mea volatile a me nā ʻāpana non-volatile. ʻO ka ATR essential oil (ATEO) ka mea i manaʻo ʻia ʻo ia ka mea ikaika o ATR, a ʻo ka ʻike o ATEO ʻo ia wale nō ka hōʻailona no ka hoʻoholo ʻana i ka ʻike ATR. I kēia manawa, aia nā noiʻi like ʻole e pili ana i nā ʻāpana volatile a ʻoi aku ka liʻiliʻi o ka noiʻi ʻana i nā ʻāpana non-volatile. He paʻakikī nā mea hoʻoheheʻe, a ʻo nā ʻano kumu nui he phenylpropanoids (phenylpropanoids maʻalahi, lignans a me coumarins) a me nā terpenoids (monoterpenes, sesquiterpenes, diterpenoids a me triterpenes). ʻO nā ʻāpana non-volatile ka nui o nā alkaloids, aldehydes a me nā waikawa, nā quinones a me nā ketones, nā sterols, nā amino acids, a me nā haʻahaʻa. ʻO nā hopena o ka ATR chemical composition study e kōkua i ka hoʻomohala ʻana i kāna noiʻi maikaʻi.
ʻO ka haku mele ʻana
Ua hoʻohana nā mea noiʻi i nā ʻenehana hoʻāʻo analytical e like me ka chromatography a me GC-MS e kālailai i nā ʻāpana kemika o ATR mai nā kumu like ʻole, nā pūʻulu ʻokoʻa, nā ʻano unuhi ʻokoʻa a me nā ʻāpana like ʻole. ʻO nā haʻawina mua i hōʻike ʻia ʻo nā mea kemika nui i loko o ka ATR he mau aila volatile, ʻo ia ka hōʻailona koʻikoʻi no ka loiloi maikaʻi o ATR. ʻO ka α-Asarone a me ka β-asarone i helu ʻia no 95% o nā aila volatile ATR a ua ʻike ʻia he mau mea kikoʻī (Helu 1) (Lam et al., 2016a). Hoʻopaʻa ka "Pharmacopoeia of The People's Republic of China" (2020 Edition) ʻaʻole pono ka emi o ka ʻaila hinu o ATR ma lalo o 1.0% (mL/g). I kēia manawa, ʻike ʻia nā ʻano mea ʻaila volatile ma ATR
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ʻO ka ʻaila ʻala ʻala oud Branded no ke kukui a me ke kopa e hana ana i nā diffuser kūʻai nui i ka aila nui hou no nā mea hoʻoheheʻe puhi ʻohe.
He lau nahele ka Perilla. Hoʻohana ʻia ka lau a me ka ʻanoʻano no ka hana lāʻau.
Hoʻohana ʻia ʻo Perilla no ka mālama ʻana i ka hānō. Hoʻohana ʻia ia no ka nausea, ka lā, ka hoʻoulu ʻana i ka hou, a me ka hoʻēmi ʻana i ka ʻiʻo.
I nā meaʻai, hoʻohana ʻia ka perilla i mea ʻono.
I ka hana ʻana, hoʻohana ʻia ka aila hua perilla ma ke kālepa ʻana i ka hana ʻana i nā varnish, dyes, a me nā inika.
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ʻO ka ʻaila ʻala ʻala oud Branded no ke kukui a me ke kopa e hana ana i nā diffuser kūʻai nui i ka aila nui hou no nā mea hoʻoheheʻe puhi ʻohe.
He mea kanu ʻo Angelica. Hoʻohana ʻia ke aʻa, ka ʻanoʻano, a me nā hua i ka lāʻau lapaʻau.
Hoʻohana ʻia ʻo Angelica no ka ʻeha o ka puʻuwai, ke kinoea ʻōpū (flatulence), pau ka ʻai (anorexia), ka ʻāʻī ʻana, nā pilikia o ke kahe ʻana, "ihu kahe" (ka hanu hanu), ka makaʻu, ka maʻi ahulau, a me ka pilikia hiamoe (insomnia).
Hoʻohana kekahi mau wahine i ka angelica e hoʻomaka i ko lākou manawa menstrual. I kekahi manawa, hana ʻia kēia i mea e hoʻohālua ai.
Hoʻohana pū ʻia ʻo Angelica e hoʻonui i ka hoʻoulu ʻana o ka mimi, hoʻomaikaʻi i ka hoʻoulu wahine, hoʻoulu i ka hana a me ka huna ʻana o ka phlegm, a pepehi i nā germs.
Hoʻopili pololei kekahi poʻe i ka angelica i ka ʻili no ka ʻeha aʻalolo (neuralgia), ʻeha hui (rheumatism), a me nā maʻi ʻili.
I ka hui pū ʻana me nā mea kanu ʻē aʻe, hoʻohana ʻia ʻo angelica no ka mālama ʻana i ka ejaculation premature.
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100% Maʻemaʻe Herbal Essential Cyperus aila no ka hana ʻana i ka ʻaila Cyperus Rotundus.
ʻO Nutgrass kahi lāʻau kaulana i hoʻohana ʻia ma waena o nā ʻano hana mālama ʻili maikaʻi. E like me Ayurveda, ua hoʻohana ʻia i nā concoctions i hoʻomākaukau ʻia e hoʻomālamalama i nā wahi ʻeleʻele a me nā mea ʻē aʻe.
Nā pōmaikaʻi…
Ua loaʻa nō hoʻi ia i loko o nā lāʻau Ayurvedic he nui no ka mālama ʻana i nā ʻōpala, nā maʻi fungal a me nā kūlana ʻili. ʻO nā ʻāpana pauka o ka aʻa Nutgrass he ikaika loa a hoʻonui ʻia me nā antioxidants, e kōkua ana e hoʻolōʻihi i ka ʻelemakule o ka ʻili i ka hana e hōʻemi i nā laina maikaʻi a me nā wrinkles. Kōkua ia i ka mālama ʻana i ka hoʻokumu ʻana o ka pigment, melanin, i ka ʻili. Ma laila e hoʻihoʻi hou ai ka ʻili o ka ʻili. ʻO ka Nutgrass he mea maʻalili i ke ʻano, ʻo kāna waiwai anti-inflammatory kōkua e hoʻomaha i ka ʻulaʻula, breakouts, a me ka ʻili inflamed. Ua hōʻoia ʻia e mālama i nā maʻi ʻili koʻikoʻi. He waiwai ia i nā ʻakika momona, nā huaora a me nā flavonoids i mea maikaʻi loa no ka ʻili a me ka lauoho. Hoʻohui kēia mau waiwai i ka ʻulaʻula o ka ʻili, a hoʻoikaika i ka lauoho me ka ʻālohilohi a me ka nui.
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ʻO ka aila Notopterygium maʻemaʻe maʻemaʻe kiʻekiʻe i hoʻohana ʻia no ka mālama Ola
Ma ke ʻano o ka hoʻokuʻu ʻana i ka makani a me ka hoʻopau ʻana i ka dampness, he nui nā mea kanu Kina kūpono. No laila, ʻo ka hoʻohālikelike ʻana i ka notopterygium me kona mau hoa me nā mea hoʻōla like e kōkua iā mākou e hoʻomaopopo maikaʻi i kēia mea kanu lāʻau.
ʻO ke kumu notopterygium a me Angelica Root (Du Huo) hiki ke hoʻomaʻemaʻe i ka makani a hoʻomaikaʻi i ka ʻeha a me ka ʻoʻoleʻa. Akā aia ko lākou mau ikaika a me nā nāwaliwali. ʻO ka mea mua me ke ʻano ikaika a me ka ʻono, kahi e loaʻa ai ka hopena antipyretic maikaʻi ma o ka hoʻoulu ʻana a me ka hiki ke piʻi. No ia kumu, he laʻau maikaʻi loa ia no nā maʻi o ke kuamoʻo a me ka ʻeha o ke kino luna a me ke kua o ke poʻo. I ka hoʻohālikelike ʻana, ʻo ka aʻa angelica me ka mana e iho ana, e hāʻawi iā ia i kahi mana hoʻōla maikaʻi ma ka rumatika o ke kino haʻahaʻa a me ka ʻeha ami ma ka wāwae, ke kua lalo, ka wāwae, a me ka ʻūhā. ʻO ka hopena, ua hoʻohana pinepine ʻia lākou i ka lāʻau lapaʻau ʻelua no ka mea ua hoʻokō nui lākou.
Notopterygium a meGui Zhi (Ramulus Cinnamomi)maikaʻi i ka hoʻokuke ʻana i ka makani a me ka wehe ʻana i ke anu. Akā, makemake kēlā mea mua i ka makani ma ke poʻo, ka ʻāʻī, a me ke kuaGui Zhiʻoi aku ka maikaʻi o ka hoʻoponopono ʻana i ka makani ma nā poʻohiwi, nā lima, a me nā manamana lima.
ʻO ka notopterygium a meFang Feng (Radix Saposhnikoviae)akamai i ka hookuke makani. Akā ʻoi aku ka ikaika o ka mea mua ma mua o Fang Feng.
ʻO nā hana lāʻau lapaʻau hou o ke kumu notopterygium
1. Loaʻa ka hopena analgesic a me nā hopena antipyretic i kāna injection. Eia kekahi, loaʻa iā ia ka inhibition i ka ʻili ʻili a me ka brucellosis;
2. He hopena hoʻokolohua anti-arrhythmic kona ʻāpana hoʻoheheʻe;
3. ʻO kāna ʻaila volatile pū kekahi i nā hopena anti-inflammatory, analgesic a me antipyretic. A hiki iā ia ke pale aku i ka pituitrin-induced myocardial ischemia a hoʻonui i ka myocardial nutritional blood flow;
4. Kona aila volatile mau inhibits lohi type hypersensitivity i ka iole.E laʻana i ka notopterygium incisum recipes ma nā lāʻau lapaʻau
Manaʻo ʻo Zhong Guo Yao Dian (Pharmacopoeia Kina) he ʻawaʻawa a ʻawaʻawa ke ʻono a me ke ʻano mahana. Uhi ia i nā meridian o ka ʻōpū a me ke kīkī. ʻO nā hana nui ka hoʻokuke ʻana i ka makani, ka hoʻopau ʻana i ke anu, ka wehe ʻana i ka wai, a me ka hoʻomaha ʻana i ka ʻeha. Hoʻohana a me nā hōʻailona kumu notopterygiumpoʻo poʻoma ke ano anu makanianu anu, rumatika, a eha eha ma ka poohiwi a me ke kua. ʻO ka dosage i ʻōlelo ʻia mai 3 a 9 grams.
1. Qiang HuoʻO Fu ZiTang mai Yi Xue Xin Wu (Nā Hōʻike Lapaʻau). Ua hui pū ʻia me Fu Zi (Aconite),Gan Jiang(Ua maloʻo maloʻoRoot), a me ZhiGan Cao(Honey Fried Licorice Root) no ka mālama ʻana i ka lolo i hoʻouka ʻia e nā pathogen anuanu o nā ʻāina ʻē, ka ʻeha o ka lolo e pā ana i nā niho, nā lālā anu, a me ka ea anuanu mai ka waha a me ka ihu.
2. Jiu Wei Qiang Huo Tang maiʻO Ci ShiNan Zhi (Ka ʻike paʻakikī). Hoʻokumu ʻia me Fang Feng, Xi Xin (Herba Asari),Chuan Xiong(aʻa lovage), etc. no ka ho'ōla ʻana i ka maʻi maʻi ʻano makani-anuanu i hui pū ʻia me ka pulu, ke anu, ke kuni, ka hou ʻole, ke poʻo,ʻāʻī ʻoʻoleʻa, a me ka eha ami oi ma na lala.
3. Qiang Huo Sheng Shi Tang mai Nei Wai Shang Bian Huo Lun (E wehewehe ana i na kanalua e pili ana i ka poino mai na kumu o loko a me waho). Hoʻohana pū ʻia me ke kumu angelica,Gao Ben(Rhizoma Ligustici), Fang Feng, etc. e ho'ōla i waho o ka makani-puʻu, poʻo a me ka ʻeha ʻeha o ka ʻāʻī, ʻawaʻawa kaumaha lalo kua, a me ke kino holoʻokoʻa eha hui.
4. ʻO Juan Bi Tang, ʻike ʻia ʻo notopterygium a meturmerichui, mai Bai Yi Xuan Fang (Precisely-koho i kauoha). Hana pū me Fang Feng, Jiang Huang (Curcuma Longa),ʻO Dang Gui(Dong Quai), a pela aku e hoopau ai i ka arthralgia o ka makani-anuanu ma ke kino o luna, ka eha ma ka poohiwi a me na lala.
5. Qiang Huo Gong Gao Tang mai Shen Shi Yao Han (He Manual waiwai oOphthalmology). Ua hui me ke kumu lovage,Bai Zhi(ʻO Angelica Dahurica), Rhizoma Ligustici, a pela aku no ka hooluolu i ka ma'i po'o ma muli o ka makani anu a i 'ole ka makani.
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ʻO ka aila ʻaila lappa ʻo Aucklandia maʻemaʻe no ke kukui a me ke kopa e hana ana i ka ʻaila diffuser kūʻai nui hou no nā diffuser puhi ʻohe.
ʻO ka Osteoarthritis (OA) kekahi o nā maʻi hui iwi degenerative lōʻihi e pili ana i ka poʻe ʻelemakule ma mua o 65.1]. ʻO ka maʻamau, ʻike ʻia nā poʻe maʻi OA me ka cartilage poino, synovium inflamed, a me nā chondrocytes eroded, kahi e hoʻoulu ai i ka ʻeha a me ka pilikia kino.2]. ʻO ka ʻeha ʻeha ma muli o ka emi ʻana o ka cartilage i loko o nā ami e ka mumū, a i ka wā e ʻeha nui ai ka cartilage hiki i nā iwi ke kuʻi kekahi i kekahi me ka hoʻomanawanui ʻole a me ka pilikia kino.3]. Hoʻopaʻa maikaʻi ʻia ke komo ʻana o nā mea hoʻolaha inflammatory me nā hōʻailona e like me ka ʻeha, ka pehu, a me ka paʻakikī o ka hui. I nā poʻe maʻi OA, loaʻa nā cytokines inflammatory, ka mea e hoʻoneʻe ai i ka cartilage a me ka iwi subchondral i loko o ka wai synovial [4]. ʻElua mau hoʻopiʻi nui i loaʻa i ka poʻe maʻi OA i ka ʻeha a me ka mumū synovial. No laila, ʻo nā pahuhopu mua o nā lāʻau lapaʻau OA i kēia manawa ʻo ka hoʻohaʻahaʻa ʻana i ka ʻeha a me ka mumū. [5]. ʻOiai ʻo nā lāʻau lapaʻau OA i loaʻa, me nā lāʻau non-steroidal a me nā lāʻau steroidal, ua hōʻoia i ka hopena i ka hoʻohaʻahaʻa ʻana i ka ʻeha a me ka mumū, ʻo ka hoʻohana lōʻihi ʻana o kēia mau lāʻau i nā hopena olakino e like me ka cardiovascular, gastro-intestinal, and renal dysfunctions [6]. No laila, pono e kūkulu ʻia kahi lāʻau lapaʻau maikaʻi me ka liʻiliʻi o nā hopena ʻaoʻao no ka mālama ʻana i ka osteoarthritis.Ke ulu nui nei nā huahana olakino kūlohelohe no ka palekana a maʻalahi hoʻi i loaʻa [7]. Ua hōʻoia nā lāʻau lapaʻau Korea kuʻuna i ka maikaʻi e kūʻē i kekahi mau maʻi ʻeha, me ka arthritis [8]. Aucklandia lappa DC. ʻike ʻia no kāna mau lāʻau lapaʻau, e like me ka hoʻonui ʻana i ke kahe o ka qi no ka hoʻomaha ʻana i ka ʻeha a me ka hoʻomaha ʻana i ka ʻōpū, a ua hoʻohana ʻia ma ke ʻano he analgesic kūlohelohe [9]. Hōʻike nā hōʻike mua e loaʻa iā A. lappa ka anti-inflammatory [10,11], analgesic [12], ka maʻi ʻaʻai [13], a me ka maʻi ʻai [14] hopena. Hoʻokumu ʻia nā hana olaola like ʻole o A. lappa e kāna mau pūhui ikaika nui: costunolide, dehydrocostus lactone, dihydrocostunolide, costuslactone, α-costol, saussurea lactone a me costuslactone [15]. Ua ʻōlelo nā haʻawina mua ua hōʻike ʻo costunolide i nā waiwai anti-inflammatory i loko o ka lipopolysaccharide (LPS), ka mea i hoʻoulu i nā macrophages ma o ka hoʻoponopono ʻana o ka NF-kB a me ke alahele protein shock heat [16,17]. Eia naʻe, ʻaʻohe haʻawina i noiʻi i nā hana kūpono o A. lappa no ka mālama ʻana i ka OA. Ua noiʻi ka noiʻi o kēia manawa i nā hopena lapaʻau o A. lappa e kūʻē i ka OA me ka hoʻohana ʻana i (monosodium-iodoacetate) MIA a me nā ʻano koʻokoʻo i hoʻokomo ʻia i ka acetic acid.Hoʻohana kaulana ʻia ka Monosodium-iodoacetate (MIA) e hana i ka nui o nā ʻano ʻeha a me nā hiʻohiʻona pathophysiological o OA i nā holoholona.18,19,20]. Ke hoʻokomo ʻia i loko o nā hui kuli, hoʻokaʻawale ʻo MIA i ka metabolism chondrocyte a hoʻoulu i ka mumū a me nā hōʻailona inflammatory, e like me ka cartilage a me ka iwi subchondral erosion, nā hōʻailona cardinal o OA [18]. ʻO ka pane wili ʻana i hoʻokomo ʻia me ka acetic acid ka mea i manaʻo nui ʻia e like me ka simulation o ka ʻeha peripheral i nā holoholona kahi e hiki ke ana ʻia ka ʻeha ʻeha [19]. Hoʻohana nui ʻia ka laina cell macrophage mouse, RAW264.7, e aʻo i nā pane kelepona i ka mumū. Ma ka ho'ā 'ana me LPS, RAW264 macrophages ho'āla i nā ala inflammatory a hūnā i kekahi mau intermediaries inflammatory, e like me TNF-α, COX-2, IL-1β, iNOS, a me IL-6 [20]. Ua loiloi kēia haʻawina i nā hopena anti-nociceptive a me nā anti-inflammatory o A. lappa e kūʻē i ka OA i loko o ke ʻano holoholona MIA, acetic acid-induced animal model, a me LPS-activated RAW264.7 cell.2. Nā mea a me nā hana
2.1. Mea kanu
ʻO ke kumu maloʻo o A. lappa DC. ua hoʻohana ʻia i ka hoʻokolohua mai Epulip Pharmaceutical Co., Ltd., (Seoul, Korea). Ua ʻike ʻia e Prof. Donghun Lee, Dept. of Herbal pharmacology, Col. of Korean Medicine, Gachon University, a ua waiho ʻia ka helu helu hōʻailona ma 18060301.2.2. ʻIke HPLC o A. lappa Extract
Lawe ʻia ʻo A. lappa me ka hoʻohana ʻana i kahi reflux apparatus (wai distilled, 3 h ma 100 °C). Ua kānana ʻia ka hopena i unuhi ʻia a hoʻopaʻa ʻia me ka hoʻohana ʻana i kahi evaporator haʻahaʻa. A. lappa extract he 44.69% ma hope o ka maloʻo maloʻo ma lalo o −80 °C. Ua alakaʻiʻia ka nānāʻana o Chromatographic o A. lappa me kahi HPLC i hoʻohuiʻia me ka hoʻohanaʻana i ka 1260 InfinityⅡ HPLC-system (Agilent, Pal Alto, CA, USA). No ka hoʻokaʻawale chromatic, ua hoʻohana ʻia ke kolamu EclipseXDB C18 (4.6 × 250 mm, 5 µm, Agilent) ma 35 °C. A huina o 100 mg o ka specimen ua diluted ma 10 mL o 50% methanol a sonicated no 10 min. Ua kānana ʻia nā laʻana me kahi kānana syringe (Waters Corp., Milford, MA, USA) o 0.45 μm. He 0.1% ka phosphoric acid (A) a me ka acetonitrile (B) ka hui o ka mobile phase a ua hoʻoheheʻe ʻia ke kolamu penei: 0-60 min, 0%; 60–65 min, 100%; 65–67 min, 100%; 67-72 min, 0% solvent B me kahi kahe kahe o 1.0 mL / min. Ua nānā ʻia ka effluent ma 210 nm me ka hoʻohana ʻana i ka nui injection o 10 μL. Ua hana ʻia ka ʻike ʻekolu.2.3. Hale a me ka hooponopono holoholona
Ua kūʻai ʻia nā ʻiole kāne Sprague-Dawley (SD) he 5 mau wiki a me nā ʻiole kāne ICR he 6 mau wiki mai Samtako Bio Korea (Gyeonggi-do, Korea). Mālama ʻia nā holoholona i loko o kahi lumi me ka hoʻohana ʻana i ka mahana mau (22 ± 2 °C) a me ka haʻahaʻa (55 ± 10%) a me ka pōʻaiapuni māmā/ʻeleʻele o 12/12 h. Ua kamaʻāina nā holoholona i ke kūlana no hoʻokahi pule ma mua o ka hoʻomaka ʻana o ka hoʻokolohua. Loaʻa i nā holoholona ka hāʻawi ad libitum o ka meaʻai a me ka wai. ʻO nā lula koʻikoʻi o kēia manawa no ka mālama ʻana a me ka mālama ʻana i nā holoholona ma ke Kulanui ʻo Gachon (GIACUC-R2019003) i mālama pono ʻia i nā kaʻina hana hoʻokolohua holoholona āpau. Ua hoʻolālā ʻia ke aʻo ʻana i ka mea noiʻi-makapō a me ka hoʻokolokolo like. Ua hahai mākou i ke ʻano hana euthanasia e like me nā alakaʻi o ke Kōmike Hoʻohālikelike Hoʻopono holoholona.2.4. MIA Injection a Lapaʻau
Ua hoʻokaʻawale ʻia nā ʻiole i 4 mau pūʻulu, ʻo ia hoʻi ka sham, control, indomethacin, a me A. lappa. Ma keʻano he anesthetized me 2% isofluorane O2 hui, ua hoʻokomoʻia nāʻiole me ka hoʻohanaʻana i ka 50 μL o MIA (40 mg / m; Sigma-Aldrich, St. Louis, MO, USA) intra-articularly i loko o nā hui kuli e alakaʻi i ka OA hoʻokolohua. Ua mālama ʻia nā lāʻau lapaʻau e like me lalo: mālama ʻia nā pūʻulu hoʻomalu a hoʻopunipuni wale nō me AIN-93G meaʻai kumu. ʻO ka hui indomethacin wale nō i hāʻawiʻia me ka indomethacin (3 mg / kg) i hoʻokomoʻia i kaʻai AIN-93G a ua hāʻawiʻia ka hui A. lappa 300 mg / kg i kaʻai AIN-93G i hoʻonuiʻia me A. lappa (300 mg / kg). Ua hoʻomau ʻia nā lāʻau lapaʻau no 24 mau lā mai ka lā o ka hoʻokomo ʻana o OA ma ka helu o 15-17 g no 190-210 g ke kaumaha o ke kino i kēlā me kēia lā.2.5. Ana Kaumaha
Ma hope o ka hoʻokomo ʻana i ka OA, ua hoʻokō ʻia ke ana ʻana i ke kaumaha o nā lālā hope o nā ʻiole me ka incapacitance-MeterTester600 (IITC Life Science, Woodland Hills, CA, USA) e like me ka mea i hoʻonohonoho ʻia. Ua helu ʻia ka puʻunaue kaumaha ma nā lālā hope: ka hiki ke amo kaumaha (%) -
Pākē Angelica Dahurica Root Extract Aila no ka lomilomi
Nā hoʻohana o Angelica
Pono e hoʻohana ʻia ka hoʻohana ʻana i nā mea hoʻohui a hoʻopaʻa ʻia e kekahi limahana mālama ola, e like me ka mea ʻai meaʻai, lāʻau lapaʻau, a i ʻole ka mea mālama ola kino. ʻAʻohe mea hoʻohui i manaʻo ʻia e mālama, hoʻōla, a pale paha i ka maʻi.
Ua nele nā hōʻike ʻepekema ikaika e kākoʻo ana i ka hoʻohana ʻana iā Angelica. I kēia manawa, ka nui o ka noiʻi maʻO Angelica archangelicaua hana ʻia ma nā ʻano holoholona a i ʻole ma nā hoʻonohonoho hoʻokolohua. Ma keʻano holoʻokoʻa, ʻoi aku ka nui o nā hoʻokolohua kanaka e pono ai i nā pono kūpono o Angelica.
Eia ka nānā ʻana i ka ʻōlelo a ka noiʻi e pili ana i ka hoʻohana ʻana iā Angelica.
Nocturia
NocturiaHe kūlana i wehewehe ʻia e like me ka pono e ala mai ka hiamoe i hoʻokahi a ʻoi aku paha i kēlā me kēia pō e mimi. Ua aʻo ʻia ʻo Angelica no ka hoʻohana ʻana i ka nocturia.
I loko o kahi noiʻi makapō ʻelua, ua hoʻokaʻawale ʻia nā mea komo me ka nocturia i hāʻawi ʻia i ke kāne ma ka hānau ʻana e loaʻa i kahiplacebo(he mea kūpono ʻole) a i ʻole kahi huahana i hana ʻia mai kaʻO Angelica archangelicalau no ewalu pule.4
Ua noi ʻia ka poʻe i komo e hahai i nā diary i ka wā a lākoumimi ʻana. Ua loiloi ka poʻe noiʻi i nā diary ma mua a ma hope o ka wā mālama. I ka pau ʻana o ke aʻo ʻana, ua hōʻike ka poʻe i lawe iā Angelica i ka liʻiliʻi o ka pō (ka pono e ala i ke aumoe e mimi) ma mua o ka poʻe i lawe i ka placebo, akā ʻaʻole nui ka ʻokoʻa.4
ʻO ka mea pōʻino, ua hana ʻia nā haʻawina ʻē aʻe e hoʻoholo ai inā hiki iā Angelica ke hoʻomaikaʻi nui i ka nocturia. Pono hou ka noiʻi ma kēia wahi.
Ka ma'i 'a'ai
ʻOiai ʻaʻohe mea hoʻohui a lāʻau lāʻau hiki ke hoʻōlamaʻi ʻaʻai, aia kekahi hoihoi iā Angelica ma ke ʻano he lapaʻau hoʻohui.
Ua aʻo ka poʻe noiʻi i nā hopena anticancer o Angelica i loko o kahi lab. Ma kekahi o ia noiʻi, ua hoʻāʻo nā mea noiʻiʻO Angelica archangelicaunuhi maka maʻi ʻaʻai umaumapūnaewele. Ua ʻike lākou e kōkua paha ʻo Angelica i ka make ʻana o ka maʻi kanesa o ka umauma, e alakaʻi ana i nā mea noiʻi e manaʻo e loaʻa paha i ka lāʻauantitumorhiki.5
Ua loaʻa i kahi haʻawina kahiko loa i hana ʻia ma nā ʻiole. Me ka ʻole o nā hoʻokolohua kanaka, ʻaʻohe mea hōʻike e hiki iā Angelica ke kōkua i ka pepehi ʻana i nā maʻi maʻi maʻi kanaka.
Ka hopohopo
Ua hoʻohana ʻia ʻo Angelica i ka lāʻau kuʻuna ma ke ʻano he lapaʻau nohopohopo. Eia naʻe, liʻiliʻi nā hōʻike ʻepekema e kākoʻo i kēia ʻōlelo.
E like me nā hoʻohana ʻē aʻe o Angelica, ʻo ka noiʻi e pili ana i ka hoʻohana ʻana i ka hopohopo i hana nui ʻia ma nā hoʻonohonoho lab a i ʻole ma nā ʻano holoholona.
Ma kahi haʻawina, hāʻawi ʻia nā ʻiole Angelica i nā ʻiole ma mua o ka hana ʻanakaumahanā hoʻokolohua. Wahi a ka poʻe noiʻi, ʻoi aku ka maikaʻi o nā ʻiole ma hope o ka loaʻa ʻana o Angelica, e lilo ia i mea lapaʻau kūpono no ka hopohopo.7
Pono nā ho'āʻo kanaka a me nā noiʻi ʻoi aku ka ikaika e hoʻoholo ai i ke kuleana kūpono o Angelica i ka mālama ʻana i ka hopohopo.
Nā Pono Antimicrobial
Ua ʻōlelo ʻia he mau waiwai antimicrobial ʻo Angelica, akā ʻaʻole i hana ʻia nā haʻawina kanaka i hoʻolālā maikaʻi ʻia e hōʻoia i kēia ʻōlelo.
Wahi a kekahi poʻe noiʻi, hōʻike ʻo Angelica i ka hana antimicrobial e kūʻē i:2
- ʻO Clostridium paʻakikī (C. ʻokoʻa)
- ʻO Clostridium perfringens
- Enterococcus faecalis
- Eubacterium limosum
- Peptostreptococcus anaerobius
- ʻO Candida albicans
Eia nō naʻe, hāʻawi ʻia ka pōʻaiapili liʻiliʻi e pili ana i ka hiki ʻana o Angelica ke kāohi i kēia mau mea a me nā hua bacteria a me nā haʻi.
Nā hoʻohana ʻē aʻe
I ka lāʻau kuʻuna,ʻO Angelica archangelicahoʻohana ʻia e mālama i nā maʻi ʻē aʻe, e like me:1
Ua kaupalena ʻia nā hōʻike ʻepekema maikaʻi e kākoʻo ana i kēia mau hoʻohana. E ʻoluʻolu e kamaʻilio me kahi mea mālama ola ma mua o ka hoʻohana ʻana iā Angelica no kēia a me nā kūlana olakino ʻē aʻe.
He aha nā hopena ʻaoʻao o Angelica?
E like me nā mea kanu a mea hoʻohui paha, hiki iā Angelica ke hana i nā hopena ʻaoʻao. Eia naʻe, ma muli o ka nele o nā hoʻokolohua kanaka, ua liʻiliʻi nā hōʻike o nā hopena ʻaoʻao o Angelica.
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ʻO ka aila ʻaila nui flos magnoliae no ka ʻaila ʻala
ʻO Magnoliae Flos kahi lāʻau lapaʻau maʻamau ma Asia. Hoʻohana ʻia ia e mālama i ka sinusitis, nasal congestion, a me ka ʻili hypersensitive. No ka mea, ua wehewehe ʻia ʻo Magonlia Flos ma ke ʻano he mea ʻala i nā kikokikona Kina kahiko, ua manaʻo mākou e hiki ke hoʻohana ʻia kāna ʻaila koʻikoʻi no ka mālama ʻana i nā maʻi kūlohelohe. ʻO nā pūnaewele Dendritic (DCs), i manaʻo ʻia he pahuhopu nui o nā immunomodulators e hoʻomalu i nā pane kūlohelohe, pāʻani i ka hana koʻikoʻi i ka pane kūlohelohe adaptive. Ma kēia haʻawina, ua hoʻemi ka ʻaila nui o Magnoliae Flos (MFEO) i ka hana ʻana o nā cytokines TNF-α, IL-6, a me IL-12p70 i loko o ka lipopolysaccharide (LPS) -stimulated DCs. Ua hoʻopaʻa pū ʻia i nā māka ʻili MHC II, CD80, a me CD86 i nā DC i hoʻoulu ʻia e LPS. Ua hōʻike ʻia nā hiʻohiʻona holoholona i ka 2,4-Dinitro-1-fluorobenzene (DNFB) e hoʻoulu ai i kahi pane hypersensitivity hoʻopili ʻia ua kāohi ʻia ma hope o ka mālama ʻana me MFEO. Eia kekahi, ua kāohi ʻo MFEO i ka hoʻokomo ʻana o nā cell T i nā pepeiao o nā ʻiole DNFB. No ka ʻimi ʻana i kāna mau pūhui bioactive, ua kālailai ʻia nā ʻāpana o MFEO me ka hoʻohana ʻana i ke kinoea chromatography (GC) a me ka GC-mass spectrometry. Ua hōʻike ʻia nā hopena ʻo nā pūhui nui i MFEO he camphor a me 1,8-cineole. Ua hōʻoia ʻia nā bioassays DC hou i kēia mau pūhui i kaohi nui i ka hana cytokine ma LPS-induced DCs. No laila, ua hōʻike mākou e hōʻike ana ʻo MFEO i kahi hopena immunosuppressive ma vivo a me in vitro, a ʻo camphor a me 1,8-cineole paha nā mea nui e pili ana i kāna hiki immunosuppressive. Hōʻike nā ʻike he hiki ke hoʻomohala ʻia ka MFEO ma ke ʻano he immunosuppressant hou no nā maʻi nui.
