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100% Maʻemaʻe Eucommiae Foliuml Aila Pono No ka mālama ʻili

wehewehe pōkole:

Eucommia ulmoides(EU) (kapa mau ʻia ʻo "Du Zhong" ma ka ʻōlelo Kina) no ka ʻohana o Eucommiaceae, kahi ʻano o ka lāʻau liʻiliʻi maoli no Kina Waena [1]. Hoʻoulu nui ʻia kēia mea kanu ma Kina ma ke ʻano nui ma muli o ka nui o ka lāʻau lapaʻau. Ma kahi o 112 mau pūhui i hoʻokaʻawale ʻia mai EU mai nā lignans, iridoids, phenolics, steroids, a me nā pūhui ʻē aʻe. Ua hōʻike ʻia ke ʻano lāʻau lapaʻau o kēia mea kanu (e like me ke kī ʻono). ʻO ka lau o EU he hana kiʻekiʻe e pili ana i ka cortex, ka pua, a me ka hua [2,3]. Ua hōʻike ʻia nā lau o EU e hoʻonui i ka ikaika o nā iwi a me nā ʻiʻo kino [4], no laila ke alakaʻi nei i ka lōʻihi o ke ola a me ka hoʻoulu ʻana i ka momona i loko o ke kanaka [5]. Ua hōʻike ʻia ke kumu kī maikaʻi i hana ʻia mai ka lau o EU e hōʻemi i ka momona a hoʻomaikaʻi i ka metabolism ikehu. Ua hōʻike ʻia nā pūhui Flavonoid (e like me rutin, chlorogenic acid, ferulic acid, a me caffeic acid) e hōʻike i ka hana antioxidants i nā lau o EU [6].

ʻOiai ua lawa nā palapala e pili ana i nā waiwai phytochemical o EU, he kakaikahi naʻe nā noiʻi e pili ana i nā waiwai lāʻau lapaʻau o nā pūhui like ʻole i unuhi ʻia mai nā ʻili, nā ʻanoʻano, nā kumu a me nā lau o EU. E wehewehe ana kēia pepa loiloi i ka ʻike kikoʻī e pili ana i nā pūhui like ʻole i unuhi ʻia mai nā ʻāpana like ʻole (ka ʻili, nā ʻanoʻano, ka ʻōpala, a me ka lau) o EU a me ka hoʻohana ʻana o kēia mau pūhui i nā waiwai hoʻoikaika olakino me nā laina ʻepekema o nā hōʻike a no laila hāʻawi i kahi mea kuhikuhi. no ka noi o EU.


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  • Hiki ke hoolako:10000 ʻāpana / ʻāpana i kēlā me kēia mahina
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    ʻO nā Lignans a me kā lākou mau mea hoʻohui nā mea nui o ka EU [7]. I kēia lā, ua hoʻokaʻawale ʻia nā lignans 28 (e like me bisepoxylignans, monoepoxylignans, neolignans, a me sesquilignans) mai ka ʻili, nā lau, a me nā hua o EU. ʻO Iridoid glycoside, kahi papa o nā metabolites lua, ʻo ia ka lua o ka mea nui o EU. Loaʻa nā Iridoids i nā mea kanu i kapa ʻia ʻo glycosides. He iwakāluakūmāhā mau iridoids i hoʻokaʻawale ʻia a ʻike ʻia mai EU (Papa 1). ʻO kēia mau pūhui i hoʻokaʻawale ʻia ʻo ia ka geniposidic acid, aucubin, a me asperuloside i hōʻike ʻia he nui nā waiwai pharmacological [810]. ʻElua mau pūhui iridoids hou, ʻo Eucommides-A a me -C, i hoʻokaʻawale ʻia i kēia manawa. ʻO kēia mau pūhui kūlohelohe ʻelua i manaʻo ʻia he conjugates o ka iridoid a me nā waikawa amino. Eia naʻe, ʻaʻole i loaʻa ka mīkini e hoʻokumu i kā lākou hana [11].

    2.2. Nā Hui Phenolic

    ʻO nā pūhui Phenolic i loaʻa mai nā meaʻai i hōʻike ʻia he hopena maikaʻi i ke olakino kanaka.12,13]. Ma kahi o 29 mau pūhui phenolic i hoʻokaʻawale ʻia a ʻike ʻia mai EU [14]. Ka huina o ka maʻiʻo o phenolic pūhui (i loko o ka gallic acid like o nā extracts a pau) ua kālailai 'ia me ka Folin-Ciocalteu phenol reagent. Ua hōʻike ʻia nā hopena o ka hoʻololi ʻana o ke kau i nā mea o kekahi pūhui a me nā antioxidants. I loko o ka makahiki hoʻokahi, ua ʻike ʻia nā mea kiʻekiʻe o nā phenolics a me nā flavonoids i nā lau o EU i ʻAukake a me Mei. ʻO Rutin, quercetin, geniposidic acid, a me aucubin i noho i loko o ka ʻike kiʻekiʻe ma Mei a i Iune.15]. Eia kekahi, kiʻekiʻe ka hana o 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging hana a me ka metala ion chelating hiki i loaʻa i loko o nā lau o EU ohi i loko o Augate. Ua hōʻike pū ʻia ka hoʻonui ʻia ʻana o nā mea antioxidants meaʻai ma Mei ke hoʻohālikelike ʻia me nā manawa ʻē aʻe o ka makahiki [15]. Ua ʻike ʻia ka lau o EU he kumu waiwai nui o nā aminoacids, nā huaora, nā minerala, a me nā flavonoids e like me quercetin, rutin, a me ka waikawa geniposidic [11,16]. He 7 flavonoids i hoʻokaʻawale ʻia maiEucommiamea kanu [17]. ʻO Rutin a me quercetin nā flavonoids nui loa.18]. ʻO Flavonoids nā pūhui koʻikoʻi i maʻamau i ke ʻano a manaʻo ʻia he metabolites lua a hana ma ke ʻano he mau ʻelele kemika, nā mea hoʻoponopono physiological, a me nā mea hoʻopaneʻe pōʻai cell.

    2.3. Nā Steroid a me nā Terpenoids

    ʻEono steroids a me ʻelima terpenoids i unuhi ʻia a hoʻokaʻawale ʻia mai EU. Aia kēia mau meaβ-sitosterol, daucosterol, ulmoprenol, betalin, betulic acid, ursolic acid, eucommidiol, rehmaglutin C, a me 1,4α,5,7α-tetrahydro-7-hydroxymethyl-cyclopenta[c]pyran-4-carboxylic methyl ester i hoʻokaʻawale ʻia mai ka ʻili o EU [19]. Ua hoʻokaʻawale ʻia ʻo Loliolide mai nā lau [20].

    2.4. Polysaccharides

    Ua hōʻike ʻia nā polysaccharides mai EU no 15 mau lā ma ke ʻano o 300-600 mg / kg e hōʻike i nā hopena pale i nā puʻupaʻa e like me ka nānā ʻana e ka malonaldehyde a me nā pae glutathione ma hope o ka hoʻoheheʻe ʻana i ka renal.21]. Ua hōʻike pū ka nānā ʻana i ka histological i nā mea antioxidative. ʻO nā unuhi mai ka ʻili o EU e hoʻohana ana i ka 70% ethanol i hōʻike pū i nā hopena pale i ka cadmium ma 125-500 mg/kg [22]. Ua hōʻike pū ka nānā ʻana i ka histological i ka hui pū ʻana me EUPanax pseudoginsengma 25% a me 50% kaumaha, no nā pule ʻeono ma ka nui o ka nui o 35.7-41.6 mg/kg i hoʻokō i nā hopena pale māmā ma ka glomerular filtration rate [8]. Ua hoʻokaʻawale ʻia ʻelua polysaccharides hou mai EU, ʻo ia ka eucomman A a me B [23].

    2.5. ʻO nā mea ʻē aʻe a me nā mea kemika

    Ua hoʻokaʻawale ʻia nā ʻakika amino, nā microelements, nā huaora, a me nā momona momona mai EU.17,2123]. ʻO Sun et al. ua ʻike pū i nā pūhui hou e like me ka n-octacosanoic acid, a me ka tetracosanoic-2,3-dihydroxypropylester mai EU [24].

    ʻO ka hui ʻana o ka ʻaila momona i unuhi ʻia mai ka hua o EU ua hōʻike i nā ʻano ʻokoʻa o ka polyunsaturated fatty acid e like me linoleic acid, linolenic acid (56.51% o ka nui o nā momona momona, TFAs), a me linolelaidic acid (12.66% o TFAs). I kēia manawa, ʻo ka ʻakika momona monounsaturated nui i hoʻokaʻawale ʻia mai ka hua i ʻike ʻia ʻo ia ka waikawa isoleic (15.80% o nā TFA). ʻO nā ʻakika momona momona nui i hoʻokaʻawale ʻia ʻo ia ka palmitic acid a me ka stearic acid e hōʻike ana i ka 9.82% a me 2.59% o TFA, kēlā me kēia.








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